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Premature rupture of membranes (PROM), or pre-labor rupture of membranes, is a condition that occurs in pregnancy. It is defined as rupture of membranes (breakage of the amniotic sac) more than 1 hour before the onset of labor.〔 The sac (consisting of 2 membranes, the chorion and amnion) contains amniotic fluid, which surrounds and protects the fetus in the uterus (womb). After rupture, the amniotic fluid leaks out of the uterus through the vagina. This is informally known as one's "water breaking". Women with PROM usually experience a painless gush of fluid leaking out from the vagina, but sometimes a slow steady leakage occurs instead. When premature rupture of membranes occurs at or after 37 weeks completed gestational age (at term), there is minimal risk to the fetus and labor typically starts soon after. If rupture occurs before 37 weeks, called preterm premature rupture of membranes (PPROM), the fetus and mother are at greater risk for complications. PPROM causes one-third of all preterm births, and babies born preterm (before 37 weeks) can suffer from the complications of prematurity, including death. Open membranes provide a path for bacteria to enter the womb and puts both the mother and fetus at risk for life-threatening infection. Low levels of fluid around the fetus also increase the risk of the umbilical cord compression and can interfere with lung and body formation in early pregnancy.〔 Women who experience premature rupture of membranes should be evaluated promptly in the hospital to determine if a rupture of membranes has indeed occurred, and to be treated appropriately to avoid infection and other complications. == Classification == * Premature rupture of membranes (PROM): when the fetal membranes rupture early, at least one hour before labor has started. * * Prolonged PROM: a case of premature rupture of membranes in which more than 24 hours has passed between the rupture and the onset of labor. * * Preterm Premature Rupture of Membranes (PPROM): premature rupture of membranes that occurs before 37 weeks. * * * Midtrimester PPROM or Pre-viable PPROM: premature rupture of membranes that occurs before 24 weeks completed gestational age of the fetus. Before this age, the fetus cannot survive outside of the mother's womb. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Premature rupture of membranes」の詳細全文を読む スポンサード リンク
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